Saturday, February 15, 2020
Comparison matrix Essay Example | Topics and Well Written Essays - 1000 words
Comparison matrix - Essay Example This type of learning transcends to a more interconnected view of the universe [where] knowledge is seen as an abstract whole to be accessed through inquiry of themes, issues, experiences, and problems (Mathison and Freeman, 1997). This approach to social studies learning also encourages discussion, critical thinking, creativity and decision making which is applicable in a real world setting. Its drawback is its cost because implementation of integrative learning may require an overhaul of the curriculum being used in the current K-12 system. According to the study of (Petrides et al., 2011) while textbooks provide a cost saving method to facilitate learning, textbook learning still requires more opportunities for more engagement and interaction such as ââ¬Å"in-class discussions led by students, supported by web-based interactive technologiesâ⬠(41). Compared to integrative learning, textbook learning is very limited as the interpretation of the universe is limited only to the viewpoint of the author and does not provide the opportunity for application, comparison and discussion of the text. c) Commercially purchased social studies learning ââ¬â commercially purchased social studies learning such as technology assisted teaching medium (DVD tutorials, online learning) became more versatile today than they were first introduced, it still cannot facilitate critical reflection and decision making due to the limitation of the medium (Rose and Fernlund, 1997). Unlike the integrative method of social studies learning where a student can infer to various discipline in synthesizing his or her interpretation of the universe, commercially purchased social studies learning are only limited to the pre-set curriculum of the program purchased. Online learning may provide interaction but the coverage of discussion is not as comprehensive compared to integrative mode of learning. Commercially purchased social studies learning can also be costly
Sunday, February 2, 2020
Jazz & Rock in the Soviet Block Essay Example | Topics and Well Written Essays - 1000 words
Jazz & Rock in the Soviet Block - Essay Example They were seen as thugs and hooligans revolting and siding with the capitalist west. For instance, outward appearance was seen to be double oppositionist. This explains why sixties teenagers enjoyed the illusion of seeing themselves as revolutionaries by simply wearing blue jeans keeping long hair. A different paradoxical aspect is that rock movement during its promising phases stood at the heart of dynamic artistic amateur by embracing a wide activity range like acting, puppetry, ballet movement etc. thus integrating a few criticism elements which had been denied expression in other public life spheres (Anna Szemere, Some Institutional Aspects of Pop and Rock in Hungary, Pp 125). Rock and jazz verse structuresà are known to influence individual actions within a common activity situation. This kind of musical progression focuses on both community and individuality. For the soviet youth it had no comparison. Rock music gradually evolved into essential freedom and self expression ing redient. It was viewed by its lovers as a political action companion rather than a being just a driver. This was especially because it unfolded from the west. Many rock ââ¬Ënââ¬â¢ roll musicians adhered to west anti war movement because of its rebelliousness appeal rather than political goals.à Rock music engendered opposing the authority, specifically when it was tied to rigid political ideologies restricting freedom of expression (Yuri Pelyushonok, Strings For a Beatle Bass, Pp. 8-17). Rock and jazzà played an important role inà subverting the Soviet Union political order. This unique genre of music undermined Soviet authority and humanized the West. It helped to alienate the young generation from oppressive political systems and sparked a revolution. It was achieved through use of... This essay mostly discusses on how the youth lost interest in the Soviet unshakeable ideals of communism. The Soviet youth no longer thought of English-speaking people as enemies. The essay describes how in the process of jazz and rock music development in the USSR the Communists had lost two young generations. The impact and power of music as a revolutionary act is a main focus of this essay, such change was incredible and remarkable in the Soviet Block. Even if some people were no rock or jazz fans due to political reasons, since the political system was against it, by merely having to listen to music was disobedience by itself. Active participation by extension made an individual an active agent working against the soviet regime. The researcher also mentiones that some of the dedicated writers and composers went to greater lengths of concealing their dissent and discusses impacts and effects of it. This was given a code name, ââ¬ËRocking the Wall.ââ¬â¢ Either way, the music reached its audience and the message was well received. Some songs would be indirectly talking about the west or the United States or sometimes capitalism. To the music fans this was coded message which was obviously ridiculing and criticizing the soviets and their communist ideologies. To conclude, the researcher sums up that the communist regimes inability curb, replace, eradicate, or assimilate rock music influence probably helped in ensuring that the population would one day turn against totalitarianism.
Saturday, January 25, 2020
Phases Of A Cell Cycle Biology Essay
Phases Of A Cell Cycle Biology Essay Interphase is a part of the cell cycle in which the cell reproduces more DNA, it is the time when a cell accomplishes the most this is the time that the cell is preparing to divide. It is duplicating its organells and increasing the amount of cytoplasm it has in order to undergo cell division interphase constitutes the longest period of the cell cycle and is divided into three successive phases. G1 phase S phase G2 phase 2.1.1. G1 Phase: The first part of the inter phase is G1. In G1phase the cellular metabolic rate is high in which cell normally grows in size. And synthesis of m-RNA, t-RNA, r-RNA and proteins occur. This phase involves accumulation and synthesis of specific enzymes needed to control DNA-synthesis and production of DNA base unit so that the supply is at hand when synthesis being. 2.1.2. S Phase: The S phase is the intermediate phase between G1growth phase (gap-1) and G2 growth phase (gap-2).During the portion of cell cycle the DNA molecule are actually duplicated to produce two similar daughter cells. 2.1.3. G2 Phase: During the gap between DNA synthesis and mitosis, the cell will continue to grow. It is also called pre-mitotic phase. In this phase energy is stored for chromosome movement. Mitotic specific protein RNA and microtubule subunit are synthesis. 2.2. Mitotic Phase: This phase involves the division of nucleus and division of cytoplasm. At this stage the growth and protein production stop. All of the cell cycle focused on the complex and orderly division into two similar daughter cells. Mitosis is much shorter than inter phase. Lasting phase only one two hours. As in both G1 and G2, there is a checkpoint in the middle of mitosis that ensures the cell is ready to complete cell division actually stages of mitosis can be viewed at animal cell mitosis. 3. Mitosis: It is a process of nuclear and cell division in which the numbers of chromosomes in daughter cells are same as that of parent cell. 4. Phases of Mitosis: Mitosis is a continuous process which has two phases. Karyokinesis Cytokinesis 4.1. Karyokinesis: This phase involves the nuclear division .Animal cell has a special structure for cell division called centriole. At the start of mitosis centriole is divided into two pairs. Each pairs migrate to the opposite side of the nucleus thus forming two poles of the dividing cell. The microtubules including aster and spindle are called mitotic apparatus. There size is larger than nucleus. The function of the mitotic apparatus is to attach and capture chromosomes, align them correctly and separate them so that equal distribution of chromosomes should take place. The microtubules are set of fibers which are three in number. They originate from each pair of centrioles. One set of microtubules is called astral microtubules which form aster outward. The other two sets form the spindle in which one is kinetochore microtubules and other is polar microtubules and other is polar microtubules. 4.1.1. Stages of Karyokinesis: Karyokinesis can be divided into four stages. Prophase Metaphase Anaphase Telophase 4.1.1.1. Prophase: Chromosomes can not be seen in the interphase stage even by electron microscope. However by using some special stains chromatin network of fine threads can be seen which is called chromatin. The following events take place in prophase. Nuclear envelope along with nucleoli disappear Centrioles completely migrate towards their poles Mitotic apparatus is organized Cytoplasm becomes more viscous The chromatin material get condensed by folding and chromosomes appear as thin threads and eventually become thick consisting of two chromatids attached with centromere 4.1.1.2. Metaphase: At metaphase chromosomes have become completely thick consisting of chromatid. These chromatids are attached to centromere. The Cells has special area the kinetochore where kinetochore fibres of mitotic apparatus attach. The kinetochore fibers of spindle are attached to kinetochore region of chromosomes and align them at the equator of the spindle forming equatorial plate or metaphase plate. Each kinetochore gets two fibers each from opposite poles. 4.1.1.3. Anaphase: It is very important phase of mitosis. The kinetochore fibers of spindle contract toward their respective poles exert force which separates the two chromatids from centromere. In this way two sister chromatids are formed. Half of them move to one pole and other half towards other pole. 4.1.1.4. Telophase: As the chromosomes reach to their respective pole telophase starts. The chromosome starts unfolding and become chromatin material. Mitotic apparatus starts disappearing while nucleus and nuceolic appears and thus two nucleoli are formed at each pole of the cell. 4.2. Cytokinesis: Cytokinesis is a phase of the mitosis in which whole of the cell divides. At this phase the astral microtubules send signals to equatorial region of cell which activate action and myosin to form contractile ring. This contractile rings form cleavage furrow in the center of cells which get deepens gradually and ultimately divide the parent cell into two daughter cells. 5. MEIOSIS: Meiosis is a special type of cell division in which the numbers of chromosomes in daughter cells are reduced to half as compare to parent cell. In animals it occurs in diploid cells at gamete formation while in plants it takes place at spore formation at gamete formation. Meiosis can take place in two divisions Meiosis I Meiosis II The first meiotic division is reduction division and second meiotic division is like that of mitosis. After two divisions diploid cell produce four haploid cells. 5.1. Stages of Meiosis I: Meiosis I is further divided into four sub-stages as following Prophase I Metaphase I Anaphase Telophase 5.1.1. Prophase I: Prophase I is a very long phase. The chromosomes in this phase behave like the homologous pairs which is different as that from mitosis. The similar chromosomes are called homologous chromosomes. Prophase I is divided into five sub stages. Leptotene Zygotene Pachytene Diplotene Diakinesis 5.1.1.1. Leptotene: At this stage the chromosomes appear as very long narrow thread and the size of nucleus increase and homologous chromosomes become closer. 5.1.1.2. Zygotene: First essential phenomenon of meiosis i.e. pairing of homologous chromosomes called synapsis starts. This pairing is highly specific and exactly pointed, but with no definite starting point. At this phase nuclei also disappears. Each paired but no fused complex structure is called bivalent or tetrad. 5.1.1.3. Pachytene: The pairing of homologous chromosomes is completed. Chromosomes become more and more thick. Each bivalent has four chromatids, which wrap around each other. Non-sister chromatids of homologous chromosomes exchange their segments due to chiasmata formation. During the process called crossing over. In this way reshuffling of genetic materials occur, which produces recombination. 5.1.1.4. Diplotene: The next stage of meiosis is diplotene where bivalents are distinct and contracted. During this phase the chiasmata of each bivalent undergoes terminalization that are the movement of two homologous chromosomes to the two ends. During the stage of prophase due to chromosome contraction they are very distinct as visible bivalent structure. 5.1.1.5. Diakinesis: Next phase is diakinesis where the chiasmata are fully terminalized and the two chromosomes remain together though fully terminalized. 5.1.2. Metaphase I: Nuclear membrane disorganize at the beginning of this phase. Spindle fibres originate and the kinetochore fibres attach to the kinetochore of the homologous chromosomes from each pole and arrange bivalent at the equator. The sister chromatids of individual chromosomes in bivalent behave as a unit. 5.1.3. Anaphase I: In this succeeding anaphase that is Anaphase I, the homologous centromeres move towards opposite direction of the pole. The centromere of each chromosome remains intact. The chromosome being separated there is no chaismata at this stage. 5.1.4. Telophase: Nuclear membranes organize around each set of chromosomes at two poles. Nucleoli reappear thus two nuclei each with half number of chromosome is formed, later on, cytoplasm divides thus terminating the first meiotic division. 6. Summary: Each cell cycle has two phase- interphase and mitotic phase. Inter phase is highly metabolic phase and subdivided into G1, S, G2 phases. Dividing phase involves the division of nucleus and division of cytoplasm. Mitosis is an equational cell division occurs in somatic cells producing two cells of the same chromosomes number of parent cell. Karyokinesis occurs in four phase à ¢Ã ¢Ã¢â¬Å¡Ã ¬prophase, anaphase, metaphase, telophase and is followed by cytokinesis. Meiosis is a reductional cell division occurs in germ cells producing four cells of half chromosomes number from that of parent cell, Nucleus divides twice in meiosis. Prophase I is of longer duration with substages leptotene, zygotene, pachytene. diplotene, diakinesis and is characterized by bivalent formation and crossing over through chaismata formation.
Friday, January 17, 2020
Case 1
Case Analysis 1: Hightone Electronics, Inc. Identification Information: This case analysis is from chapter 1 of our text book, Operations Management. It is found on page 25 and titled, ââ¬Å"Hightone Electronics, Inc. â⬠Summary of the Facts of the Case: Hightone Electronics, Inc. (HEI) is an electronic components supply company founded over 50 years ago. The company has a reputation for high quality and service. HEI's simple business of supplying radio repair shops with parts has grown to include home delivery, and larger customers such as technical schools, universities, and well-known corporations.The company stocks and sells over 22,000 different items and most customers receive their order within 48 hours. George Gonzales is the operations director for HEI. He has been tasked with making operations management decisions necessary to make HEI a successful Internet-based business. Mr. Gonzales agrees that this is an important step for the future success of the company but bel ieves there is more to solving the problems of the transition to web-based than the board thinks. Case Questions: 1.Explain why operations management is critical to the success of a business. Operations management (OM) is critical to the success of a business for several reasons. OM is responsible for the decision-making and leadership process that creates the product or service the business provides. The role of OM is to take inputs such as, labor, raw materials, and technology, and turn them into finished goods or services. Other functions of the business, such as marketing, are also important. But, without OM, there would not be a product/service to market to consumers. Reid, 2-23) Why would developing an Internet-based business require different operations consideration for HEI? A traditional catalog-order business and an Internet-based catalog-order business would be very similar in general appearance. A transition to web-based ordering though, would require changes. First, the company would need to upgrade its technology. Either through outsourcing or internal servers, the company would need to create a website. The website would need to be able to handle the customer traffic without crashing.Also, the website would need to be user-friendly so as not to frustrate and turn away potential customer. Customer support personnel would need to be trained to guide customers with questions about the website. Second, and more important than the actual website, is coordinating orders so that requested goods are shipped to the proper customer. Each order transaction will not be entered by a person. Therefore, all of the information gathered by the website will need to be converted to orders easily understood by warehouse personnel.Is George Gonzales correct in his assessment that this would not be ââ¬Å"business as usualâ⬠? Yes. The core functions of the physical locations of the catalog-order business will remain mostly the same as before. They will receive o rders, and ship out goods. However, the methods of obtaining orders, customer feedback, return orders, special orders, and many other less notable but still necessary functions will change drastically. If done properly, it will most likely streamline the business, but the initial transition will be difficult. . Recall that HEI wishes to continue its reputation of high quality and service. Identify key operations management decisions that need to be considered. * Will we receive more/less orders? * If demand increases, can HEI supply the demand? * If demand decreases, can HEI ââ¬Å"weather the stormâ⬠until demand rebounds? * What new personnel will be required? * Can current employees be trained? * Do new, more technically-advanced employees need to be hired? * Can stock be reduced and operations made more lean? * Should stock be increased?How different will these decisions be for the Internet business? The major difference will be that with a lot of the web-based area of the business, work will be handled electronically and not in a physical location. This will eliminate the need for large call centers and central records keeping locations. A few servers could hold all the information once held by an entire department such as sales, accounting, customer service, etc. This also changes the focus from managing many low-skilled employees to fewer moderate-to-high-skilled employees. Case 1 chapter 2 CHARTING A COMPANYââ¬â¢S DIRECTION: VISION AND MISSION, OBJECTIVES, AND STRATEGY McGraw-Hill/Irwin Copyright à © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. LO1 Grasp why it is critical for company managers to have a clear strategic vision of where a company needs to head and why. LO2 Understand the importance of setting both strategic and financial objectives. LO3 Understand why the strategic initiatives taken at various organizational levels must be tightly coordinated to achieve companywide performance targets.LO4 Become aware of what a company must do to achieve operating excellence and to execute its strategy proficiently. LO5 Become aware of the role and responsibility of a companyââ¬â¢s board of directors in overseeing the strategic management process. 2-2 What Does the Strategy-Making, Strategy-Executing Process Entail? 1. 2. 3. 4. Developing a strategic vision Setting objectives Crafting a strategy Implementing and executing the chosen strat egy 5. Monitoring developments, evaluating performance, and initiating corrective adjustments 2-3 FIGURE 2. 1 The Strategy-Making, Strategy-Executing Process 2-4 TABLE 2. Factors Shaping Decisions in the Strategy-Making, Strategy-Executing Process Internal Considerations Does the company have an appealing customer value proposition? What are the companyââ¬â¢s competitively important resources and capabilities and are they potent enough to produce a sustainable competitive advantage? Does the company have sufficient business and competitive strength to seize market opportunities and nullify external threats? Are the companyââ¬â¢s prices and costs competitive with those of key rivals? Is the company competitively stronger or weaker than key rivals? External ConsiderationsDoes sticking with the companyââ¬â¢s present strategic course present attractive opportunities for growth and profitability? What kind of competitive forces are industry members facing and are they acting to enhance or weaken the companyââ¬â¢s prospects for growth and profitability? What factors are driving industry change and what impact on the companyââ¬â¢s prospects will they have? How are industry rivals positioned and what strategic moves are they likely to make next? What are the key factors of future competitive success and does the industry offer good prospects for attractive profits for companies possessing those capabilities? 2-5Factors Shaping Strategic Decisions External Considerations What are the industryââ¬â¢s economic characteristics? How strong are the competitive forces at play? What forces are driving change in the industry? What market positions do rivals occupy and what moves are they likely to make next? What are the key factors for future competitive success? What are the companyââ¬â¢s external opportunities? 2-6 Factors Shaping Strategic Decisions Internal Considerations How well is the present strategy working? What are the companyââ¬â¢s competiti vely valuable resources, capabilities, and internal weaknesses? Are the companyââ¬â¢s prices and costs competitive?Is the company competitively stronger or weaker than key rivals? 2-7 Stage 1: Developing a Strategic Vision, a Mission, and Core Values Strategic Vision Is top managementââ¬â¢s views about the firmââ¬â¢s direction and future product-market-customer-technology focus Provides a panoramic view of ââ¬Å"where we are goingâ⬠Is distinctive and specific to a particular organization Avoids use of innocuous uninspiring language that could apply to most any firm Definitively states how the companyââ¬â¢s leaders intend to position the firm beyond where it is today 2-8 Characteristics of Effectively Worded Vision Statements GraphicPaints a picture of the kind of firm that management is trying to create Flexible Is not so focused that it makes it difficult to adjust Feasible Is within the realm of what is possible Directional Is forward looking to change Desirable Indicates why the directional path makes sense Focused Is specific enough to provide guidance in decision making Easy to Communicate Can be explained in simple terms 2-9 TABLE 2. 2 Characteristics of Effectively Worded Vision Statements Paints a picture of the kind of company that management is trying to create and the market position(s) the company is striving to stake out.Is forward looking; describes the strategic course that management has charted and the kinds of product-market-customer-technology changes that will help the company prepare for the future. Is specific enough to provide managers with guidance in making decisions and allocating resources. Is not so focused that it makes it difficult for management to adjust to changing circumstances in markets, customer preferences, or technology. Is within the realm of what the company can reasonably expect to achieve. Indicates why the directional path makes good business sense.Is explainable in 5 to 10 minutes and, ideally, ca n be reduced to a simple, memorable ââ¬Å"sloganâ⬠Graphic Directional Focused Flexible Feasible Desirable Easy to communicate 2-10 TABLE 2. 3 Common Shortcomings in Company Vision Statements Short on specifics about where the company is headed or what the company is doing to prepare for the future. Doesnââ¬â¢t indicate whether or how management intends to alter the companyââ¬â¢s current product-market-customer-technology focus. So all-inclusive that the company could head in most any direction, pursue most any opportunity, or enter most any business.Lacks the power to motivate company personnel or inspire shareholder confidence about the companyââ¬â¢s direction. Provides no unique company identity; could apply to firms in any of several industries (including rivals operating in the same market arena). Doesnââ¬â¢t say anything specific about the companyââ¬â¢s strategic course beyond the pursuit of such distinctions as being a recognized leader, a global or world wide leader, or the first choice of customers. Vague or incomplete Not forward looking Too broad Bland or uninspiring Not distinctive Too reliant on superlatives 2-11Concepts and Connections 2. 1 Examples of Strategic Visionsââ¬âHow Well Do They Measure Up? 2-12 Concepts and Connections 2. 1 Examples of Strategic Visionsââ¬âHow Well Do They Measure Up? 2-13 Examples of Vision Statements To be the global leader in customer value. Provide a global trading platform where practically anyone can trade practically anything. Red Hat To extend our position as the most trusted Linux and open source provider through a complete range of enterprise software, a powerful Internet platform, and associated support and services. 2-14 Core Concept Strategic Inflection PointsA change in vision is required when it becomes evident to management that the industry has changed in a significant way that renders the companyââ¬â¢s current vision obsolete. 2-15 The Importance of Communicating the St rategic Vision An engaging, inspirational vision Challenges and motivates the workforce Articulates a compelling case for ââ¬Å"where we are going and whyâ⬠Evokes positive support and excitement Arouses a committed organizational effort to move in a common direction 2-16 Expressing the Essence of the Vision in a Slogan Nike To bring innovation and inspiration to every athlete in the world The Mayo ClinicThe best care to every patient every day Greenpeace To halt environmental abuse and promote environmental solutions. 2-17 Why a Sound, Well-Communicated Strategic Vision Matters 1. It crystallizes senior executivesââ¬â¢ own views about the firmââ¬â¢s long-term direction. 2. It reduces the risk of rudderless decision making by management at all levels. 3. It is a tool for winning the support of employees to help make the vision a reality. 4. It provides a beacon for lower-level managers in forming departmental missions. 5. It helps an organization prepare for the future. 2-18 Strategic Vision versus Mission StatementA strategic vision concerns a firmââ¬â¢s future business pathââ¬âââ¬Å"where we are goingâ⬠Markets to be pursued Future product/ market/customer/ technology focus The mission statement of a firm focuses on its present business purposeââ¬âââ¬Å"who we are and what we doâ⬠Current product and service offerings Customer needs being served 2-19 Developing a Company Mission Statement Ideally, a company mission statement is sufficiently descriptive to: Identify the companyââ¬â¢s products or services. Specify the buyer needs it seeks to satisfy. Specify the customer groups or markets it is endeavoring to serve.Specify its approach to pleasing customers. Give the company its own identity. 2-20 Example of a Mission Statement The mission of Trader Joeââ¬â¢s is to give our customers the best food and beverage values that they can find anywhere and to provide them with the information required for informed buying decisi ons. We provide these with a dedication to the highest quality of customer satisfaction delivered with a sense of warmth, friendliness, fun, individual pride, and company spirit. 2-21 Examples of Mission Statements To help people and businesses throughout the world realize their full potential.To organize the worldââ¬â¢s information and make it universally accessible and useful. 2-22 Strategic Mission, Vision, and Profit Firms sometimes state that their mission is to simply earn a profit. Profit is the obvious intent of every commercial enterprise. Profit is not ââ¬Å"who we are and what we do. â⬠Profit is more correctly an objective and a result of what a firm does. 2-23 Linking the Strategic Vision and Mission with Company Values CORE CONCEPT A firmââ¬â¢s values are the beliefs, traits, and behavioral norms that the firmââ¬â¢s personnel are expected to display in conducting the firmââ¬â¢s business and pursuing its strategic vision and mission. -24 CONCEPTS & CON NECTIONS 2. 2 ZAPPOS MISSION AND CORE VALUES Deliver Wow through Service Embrace and Drive Change Create Fun and a Little Weirdness Be Adventurous, Creative, and Open Minded Pursue Growth and Learning Build Open and Honest Relationships with Communication Build a Positive Team and Family Spirit Do More with Less Be Passionate and Determined Be Humble 2-25 Stage 2: Setting Objectives Why set objectives? To convert the strategic vision into specific performance targets To create yardsticks to track progress and measure performance Objectives should:Be well-stated (clearly worded) Be challenging, yet achievable in order to stretch the organization to perform at its full potential Be quantifiable (measurable) Contain a specific deadline for achievement 2-26 Core Concept Objectives are an organizationââ¬â¢s performance targetsââ¬âthe results management wants to achieve. 2-27 Stage 2: Setting Objectives (contââ¬â¢d) What Kinds of Objectives to Set Financial objectives Communicat e managementââ¬â¢s targets for financial performance Are lagging indicators that reflect the results of past decisions and organizational activities Relate to revenue growth, profitability, and return on investment -28 Stage 2: Setting Objectives (contââ¬â¢d) What Kinds of Objectives to Set Strategic objectives Are related to a firmââ¬â¢s marketing standing and competitive vitality Are leading indicators of a firmââ¬â¢s future financial performance and business prospects. If achieved, indicate that a firmââ¬â¢s future financial performance will be better than its current or past performance. 2-29 Core Concept The balanced scorecard is a widely used method for combining the use of both strategic and financial objectives, tracking their achievement, and giving management a more complete and balanced view of how well an organization is performing. -30 TABLE 2. 4 The Balanced Scorecard Approach to Performance Measurement Strategic Objectives â⬠¢ Winning an x percent m arket share â⬠¢ Achieving customer satisfaction rates of x percent â⬠¢ â⬠¢ â⬠¢ â⬠¢ Increase percentage of sales coming from new products to x percent Financial Objectives â⬠¢ An x percent increase in annual revenues â⬠¢ Annual increases in earnings per share of x percent â⬠¢ An x percent return on capital employed (ROCE) or shareholder investment (ROE) â⬠¢ Bond and credit ratings of x â⬠¢ Internal cash flows of x to fund new capital investment â⬠¢ Improve information systems capabilities to give frontline managers Achieving a customer defect information in retention rate of x percent x minutes Acquire x number of new â⬠¢ Improve teamwork by customers increasing the number of Introduction of x number projects involving more of new products in the than one business unit next three years to x Reduce product development times to x months 2-31 Examples of Financial ObjectivesX% increase in annual revenues X% increase annually in after-tax p rofits Profit margins of X% X% return on capital employed (ROCE) Sufficient internal cash flows to fund 100% of new capital investment 2-32 Examples of Strategic Objectives Winning an X% market share Achieving a customer retention rate of X% Acquire X number of new customers Reduce product defects to X% Introduction of X number of new products in the next three years Increase employee training to X hours/year Reduce turnover to X% per year 2-33 Examples of Company ObjectivesGeneral Motors Reduce the percentage of automobiles using internal combustion engines through the development of hybrids, range-extended electric vehicles, and hydrogen fuel cell electric engines. Reduce automotive structural costs to benchmark levels of 23% of revenue by 2012 from 34% in 2005. Reduce annual U. S. labor costs by an additional $5 billion by 2011. 2-34 Examples of Company Objectives The Home Depot Be the number one destination for professional contractors. Improve in-stock positions so customers ca n find and buy exactly what they need.Deliver differentiated customer service and the know-how that our customers have come to expect. Repurchase $22. 5 billion of outstanding shares during 2008. Open 55 new stores with 5 store relocations in 2008. 2-35 Short-Term and Long-Term Objectives Short-Term Objectives Targets to be achieved soon Milestones or stair steps for reaching long-range performance Long-Term Objectives Targets to be achieved within 3 to 5 years 2-36 The Need for Objectives at All Organizational Levels Objectives Are Needed at All Levels 1. Set business-level objectives 2.Establish functional-area objectives 3. Set operating-level objectives last Long-term objectives take precedence over short-term objectives 2-37 Stage 3: Crafting a Strategy Crafting a strategy means asking: How to attract and please customers How to compete against rivals How to position the firm in the marketplace and capitalize on attractive opportunities to grow the business How best to respond to changing economic and market conditions How to manage each functional piece of the business How to achieve the firmââ¬â¢s performance targets 2-38A Firmââ¬â¢s Strategy-Making Hierarchy A firmââ¬â¢s strategy is a collection of initiatives undertaken by managers at all levels in the organizational hierarchy Crafting strategy is a collaborative effort that: Involves managers from various levels of the organization Is rarely something only highlevel executives engage in Requires choosing among the various strategic alternatives 2-39 Concept to Action In most firms, crafting strategy is a collaborative team effort that includes managers in various positions and at various organizational levels.Crafting strategy is rarely something only highlevel executives do. 2-40 Concept to Action Corporate strategy establishes an overall game plan for managing a set of businesses in a diversified, multibusiness firm. Business strategy is primarily concerned with strengthening the firmâ⬠â¢s market position and building competitive advantage in a single business company or a single business unit of a diversified multibusiness corporation. 2-41 FIGURE 2. 2 A Companyââ¬â¢s Strategy-Making Hierarchy 2-42 Corporate Strategy versus Business StrategyCorporate strategy is orchestrated by the CEO and other senior executives and establishes an overall game plan for managing a set of businesses in a diversified, multibusiness company. Business strategy is primarily concerned with building competitive advantage in a single business unit of a diversified company or strengthening the market position of a nondiversified single business company. 2-43 The Strategy-Making Hierarchy Corporate strategy â⬠¢ Is orchestrated by the CEO and other senior executives and establishes an overall game plan for managing a set of businesses in a diversified, multibusiness company. Addresses the questions of how to capture cross-business synergies, what businesses to hold or divest, which new markets to enter, and how to best enter new marketsââ¬âby acquisition, creation of a strategic alliance, or through internal development. Business strategy Functional-area strategies â⬠¢ Is primarily concerned with building competitive advantage in a single business unit of a diversified company or strengthening the market position of a nondiversified single business company. Are concerned with the strategies specifically related to particular functions or processes within a business (marketing strategy, production strategy, finance strategy, customer service strategy, product development strategy, and human resources strategy). â⬠¢ Are relatively narrow strategic initiatives and approaches of limited scope for managing key operating units (plants, distribution centers, geographic units) and specific operating activities such as materials purchasing or Internet sales. 2-44 Operating strategies Stage 4: Implementing and Executing the Chosen StrategyManaging the strate gy execution process involves: Staffing the organization to provide needed skills and expertise. Allocating ample resources to activities critical to good strategy execution. Ensuring that policies and procedures facilitate rather than impede effective execution. Installing information and operating systems that enable personnel to perform essential activities. 2-45 Stage 4: Implementing and Executing the Chosen Strategy (conââ¬â¢d) Managing the strategy execution process involves: Pushing for continuous improvement in how value chain activities are performed.Tying rewards and incentives directly to the achievement of performance objectives. Creating a company culture and work climate conducive to successful strategy execution. Exerting the internal leadership needed to propel implementation forward. 2-46 Stage 5: Evaluating Performance and Initiating Corrective Adjustments Triggering change as needed: Monitoring new external developments Evaluating the firmââ¬â¢s progress Mak ing corrective adjustments Managing strategy is an ongoing process, not an every-now-and-then task A firmââ¬â¢s vision, objectives, strategy, and approach to strategy execution are never final -47 Corporate Governance: The Role of the Board Of Directors The Role of the Board Of Directors in the StrategyMaking, Strategy-Executing Process: 1. Oversee the firmââ¬â¢s financial accounting and reporting practices. 2. Diligently critique and oversee the companyââ¬â¢s direction, strategy, and business approaches. 3. Evaluate the caliber of senior executivesââ¬â¢ strategy-making and strategy-executing skills. 4. Institute a compensation plan for top executives that rewards them for actions and results that serve shareholder interests. 2-48 Strong Boards Lead to Good Corporate GovernanceA Strong, Independent Board of Directors: Is well informed about the companyââ¬â¢s performance Guides and judges the CEO and other top executives Has the courage to curb management actions it be lieves are inappropriate or unduly risky Certifies to shareholders that the CEO is doing what the board expects Provides insight and advice to management Is intensely involved in debating the pros and cons of key decisions and actions 2-49 Leading the Strategic Management Process The Strategic Management Process calls for six managerial actions: 1.Making sure the company has a good strategic plan 2. Stay on top of what is happening (MBWA) 3. Putting constructive pressure on organizational units to achieve good results 2-50 Leading the Strategic Management Process (contââ¬â¢d) The Strategic Management Process calls for six managerial actions: 4. Pushing corrective actions to improve both the firmââ¬â¢s strategy and how well it is being executed 5. Leading the development of better competitive capabilities 6. Displaying ethical integrity and leading social responsibility initiatives 2-51 Making Sure a Firm Has a Good Strategic PlanResponsibility of CEO Effectively communicate th e vision, objectives, and major strategy components Exercise due diligence in reviewing lower-level strategies for consistency with higher-level strategies 2-52 Staying on Top of How Well Things Are Going Stay connected to the field by managing by walking around (MBWA) Insist that top managers spend time in the trenches to exchange information and ideas through face-to-face contact with employees Prevent overly abstract thinking and getting disconnected with reality of whatââ¬â¢s happening 2-53Pushing for Good Results and Operating Excellence Fosters a resultsââ¬âoriented, high-performance culture Treat employees with dignity and respect Encourage employees to use initiative and creativity in performing their work Set stretch objectives and clearly communicate expectations Focus attention on continuous improvement Reward high performance Celebrate successes 2-54 Initiating Corrective Actions to Improve Strategy and Execution The leadership challenge of making corrective adjus tments is twofold: Deciding when adjustments are needed Deciding what adjustments to makeLeaderââ¬â¢s responsibility is to step forward and push corrective actions 2-55 Leading Social Responsibility The strength of management commitment determines whether a company will implement and execute a full-fledged strategy of social responsibility that: That protects the environment Actively participates in community affairs Supports charitable causes Supports workforce diversity and the overall well-being of employees 2-56 Displaying Ethical Integrity The CEO and other senior executives must set an excellent example in their own ethical behavior.Top management must declare unequivocal support of the companyââ¬â¢s ethical code. Top management must be prepared to act swiftly and decisively in punishing ethical misconduct. 2-57 Leading the Development of Better Competitive Capabilities Lead efforts to strengthen existing competitive capabilities Anticipate changes in customer-market req uirements Proactively build new competencies and capabilities that hold promise for building an enduring competitive edge 2-58
Thursday, January 9, 2020
Breast Cancer Susceptibility Genes BRCA1 and BRCA2 Essay
Breast cancer is the most common cancer that affects women in the United States. There are at least two majors genes (BRCA1 and BRCA2) that when they mutate can cause breast cancer. These genes can be passed from parent to child, increasing the risk of developing cancer in those child that have parent carrying these genes. BRCA1 and BRCA2 genes are located on chromosome 17 and chromosome 13 respectively. There is a 90% chance of developing breast cancer for a woman that has these mutated genes. In contrast, men carrying BRCA1 have no risk to develop breast cancer, but those carrying BRCA2 genes have high risk. It is important to note that mutations in these genes can be passed on to children by either parent. A man with a mutation is justâ⬠¦show more contentâ⬠¦Subsequently, each cell that develops from the fertilized egg will receive this mutated gene. He states that for a cancer to manifest, two mutations must occurs. In hereditary cancers, the person inherit one mutant gene . The second mutation occurs as result of a mitotic error during the many cell division that occurs in the persons lifetime. In sporadic cases both mutation occur in the persons lifetime. In sporadic cases both mutation occurs after fertilization an are acquired much later in life. From this Kudson conclude that hereditary cancers manifest at younger age and there is a higher incidence of multiple tumors, where sporadic cancers occur late in the life and usually only a single tumor occurs. The principal causes of cancer appears to be environmental agents. A good example of this is skin cancer. The condition has increased among fair skinned people who expose themselves to too much sunshine, while being very uncommon among dark skinned races (knudson 1971, cited in Ormiston, 1995). Therefore, most genetic alteration are acquired through our life time from environmental carcinogens with only a small percentage been inherited. However, inherited cancers are very important as it appears that the genes responsible for, hereditary cancer maybe the same as those involved in sporadic malignancies. There are two important type of genes responsible for the development or cancer namely tumor suppressor because their normal function isShow MoreRelatedEssay on Breast Cancer847 Words à |à 4 PagesBreast Cancer Chromosome 17 and BRCA1 Among the most common diseases affecting the female population, breast cancer develops in one of every eight American women. This means that almost 200,000 women suffer from the disease each year. Doctors would advise women to take necessary precautions, such as routine surveillance, in order to ensure a life without obtaining this disease prior to understanding any genetic linkage of breast cancer. Although many external factors contribute to breastRead MoreBrca1 And Brca2 : Factors That Affect The Risk Of Breast Cancer1589 Words à |à 7 Pages The second similarity is that both BRCA1 and BRCA2 bind to Rad5 protein that is involved in maintain the integrity of the genome (Kinzler et al, 1997). A mutation in the AT, or ATM, gene on chromosome 11 also is associated with breast cancer, and it may be much more common in the general population than BRCA1 or BRCA2 mutations. Seven percent of familial breast cancer may be associated with the AT gene mutation (Radford and Zehnbauer, 1996, cited in McCain, 1997). It is not known whether theRead MoreTaking a Look at Breast Cancer1758 Words à |à 7 PagesIntroduction Breast cancer is the most common cause of cancer-related death among females in the world. It is known for ââ¬Å"have both a genetic and non-genetic etiologyâ⬠(Milne et al., 2010). It involves a combination of several factors- such as ââ¬Å"genetic, environmental and behavioral risk factorsâ⬠- that are unique to each individual (Nickels et al., 2013). This type of cancer is represented by a malignant tumor manifested in breast cells such as the line duct and line lobules cells, just to name a fewRead More Breast Cancer Genes Essay3402 Words à |à 14 PagesSurrounding the Breast Cancer Genes The process of unraveling the mysteries of the human genome creates enormous possibilities in the world of science. Knowing where on our chromosomes a specific gene lies allows scientists to look inside the human body with more intensity than any X-ray could ever achieve. By analyzing the genetic make-up of human beings, scientists can track diseases back to their most fundamental stages. In recent years, scientists have discovered two genes that play a roleRead MoreA Study On Breast Cancer2075 Words à |à 9 PagesBreast cancer is a disease that starts when an abnormal, uncontrolled cell growth occurs in the tissues of the breast. In a healthy body, cells grow, divide, and die in an orderly way, but once a damage or a mutation happens in the genetic material of the cell (which is found in the DNA) it results in cells that do not die. They continue to grow and divide uncontrollably and form abnormal cells that the body does not need. They can also metastasize, which means they invad e other tissues through theRead MoreThe Cell Cycle Of Cancer1453 Words à |à 6 PagesCancer is a genetic disease that is caused by mutations to genes that regulate a cellââ¬â¢s functions. According to the National Ovarian Cancer Coalition, ââ¬Å"Ovarian cancer is a disease in which malignant or cancerous cells are found in the ovariesâ⬠(American Cancer Society). In other words, as the cells within the ovaries continue to grow abnormally, benign or malignant neoplasms will occur. Those cells will then outlive normal cells, and spread rapidly to other sections of the body due to the abnormalRead MoreA Right to Her Genes1451 Words à |à 6 PagesHer Genes by Susannah Gal Department of Biological Sciences State University of New York at Binghamton and Jessie W. Klein Science Department Middlesex Community College ââ¬Å"But, doctor, what should I do?â⬠Michelle was sitting in her OB-GYNââ¬â¢s office, having just confronted him with the dilemma she was facing. ââ¬Å"My mother died of breast cancer when I was little and now I find out that her mother, my grandmother, has bone cancer and my grandmotherââ¬â¢s brother and my grandfather both have lung cancer. MyRead MoreCancer Literature Review1462 Words à |à 6 Pagesis based on the Genome-wide association studies of cancer, or GWAS. GWAS is an approach to research the genetic basis of different diseases. For example, with oncology, GWAS was performed and able to identify approximately 450 genetic variants that are related to the risks, as well as provided proof of polygenic susceptibility. This review targeted on the functional basis and gene structure of cancer susceptibility. Regarding cancer, thereââ¬â¢s a pattern of relative risk or RR, thatââ¬â¢s highRead MorePrevention And Treatment Of Breast Cancer3159 Words à |à 13 Pagesvast majority of cancer deaths, metastasis is the complex process by which the cancer cells spread from the primary site to distant sites throughout the body by way of increased tumor invasiveness. Tumor cells persist in replication and may inadequately differentiate into specialized cells as they attain an aggressive manner. Given that it is among the most commonly diagnosed cancers in the United States, approximately 1 in 8 women and 1 in 1,000 men in America may develop breast cancer throughout theirRead MoreTwentieth Century is the Cancer Century1801 Words à |à 7 Pagestwentieth century has often been called the cancer century. This is because more than a hundred types of cancer have been discovered in this century, and secondly, because enormous medical efforts have been made to fight all kinds of cancer throughout the world. In the early decades of the twentieth century, cancer was considered to be a fatal disease. Although some cancers are still fatal, medical therapy has developed significantly over the years so that most cancers can be treated and cured. After decades
Tuesday, December 31, 2019
Monday, December 23, 2019
Primitive Speech Stages Of Children - 1596 Words
1. Primitive speech stage Birth to 2 years ââ¬â this is a period where the child will learn, imitate words, tries to name object, will begin to speak and emotionally react by crying or socially respond by laughing. 2. Naà ¯ve psychological stage 2 to 4 years ââ¬â Words are used as symbol are fully understood to express the objects and will expand their knowledge to identify more objects around their environment. 3. Egocentric stage 4 to 7 years ââ¬â Children will talk louder to be heard or seeking attention and rational thinking will set to solve problems or perform tasks. 4. Ingrowth stage 8 years onwards ââ¬â This is the stage where the child will speak less and internalised more using private speeches (Nixon, Aldwinckle and Gould 2003). The term ââ¬Ëscaffoldingââ¬â¢ the childââ¬â¢s behaviour as Vygotsky explains that children are often aided by us and we direct them together into achieving the purpose of any activity. For an example, in the Montessori, every day there is a walk about around the park which require the children changing their shoes to wellingtons. On return there are some who just refuse to tie their shoe laces because parents always tie their shoes lace at home. A particular child who was struggling for some time and failed was very confused and in tears. I decided to hold his hand and directed him to tie his shoe lace. From that moment onwards, the child was able to do it himself and he was very proud of his achievements as a result of ââ¬Ëscaffoldingââ¬â¢. There is otherShow MoreRelatedVygotsky And Vygotsky s Theory Of Cognitive Development Of Thought And Language Essay1060 Words à |à 5 Pagesand Language: independent processes. With the passing of time, the development of thought and language has been the object of study for psychologists such as Jean Piaget and Lev Vygotsky. The former drastically influenced the study of thought and speech with his theory of cognitive development and his clinical method. The latter also made his contribution with his sociocultural theory. Although language and thought may be analysed as associate one to the other, both of them may be considered as independentRead MoreWhat For You Is The Human Spark983 Words à |à 4 Pagesthat no there are many theories about the human spark, but that theory are not true, however, there are Known human paleontologists primitive Neanderthal as one of the strains that inhabited the earth and some are believed to be the ancestors of human sapiens s in Europe since the year six hundred thousand to three hundred and fifty years 600000-350000 .. Primitive man and has a bad reputation for being barbaric, barbaric, with a low level of intelligence, but scientists are discovering every dayRead More Caliban Portrayed as a Child in The Tempest1901 Words à |à 8 PagesCalibans speech and manners, as well as his thought, all display the very basic reactions and notions of human beings.à He is also controlled by a parent figure who comes in the form of Prospero.à An analysis of Caliban can hold him up to Piagets Theory of Cognitive Development, which focuses on the development of children.à Caliban, unquestionably, fits one of Piagets developmental stages.à Jean Piaget developed his Theory of Cognitive Senses in 1952.à According to Piaget, as children develop,Read MoreJean Piaget And Vygotsky And Language Development In Children1748 Words à |à 7 PagesVygotsky are two influential thinkers who have impacted the speech and language pathology field with their key theories. Piaget believed that there are four main st ages in a childââ¬â¢s development that lead to a child learning language. Without these stages, Piaget argues that a child cannot cognitively grow at an appropriate pace (Kaderavek, 2105, p. 18 and p. 23). However, Vygotsky argues the Social Interactionist Theory, which states children develop language through social interacting with adults whoRead More Effective Use of Dialogue in The Sacrifice of Isaac Essay1489 Words à |à 6 Pages I have diverse children moo, The which I love not halffe so well. This fayer swet child, he schereys me soo . Now cum on, Isaac, my owyn swet child;. Cume on, swete child. I love thee best Of all the children that I ever begat. à It appears that this opening speech by Abraham is designed to induce the audience to think ahead to Gods demand, by offering them a view of Abrahams love for Isaac, and Isaacs fitness as a son. The portions of this speech that I have not quotedRead MoreDevelopment Through Life Stages Essay1406 Words à |à 6 Pagesfertilised egg the size of a pin head. The collection of cells travels to the lining of the uterus where it becomes implanted. At this stage the collection of cells is called an embryo. After eight weeks, the embryo may have grown to between three and four centimetres, has a recognizable heart bear ad the beginnings of eyes, ears, a mouth, legs and arms. At this stage the growing organism is called a foetus. During the final seven months before birth, all the organs continue to develop. By twentyRead More Analysis of Athol Fugards Master Harold . . . and the Boys Essay618 Words à |à 3 Pagespredominant themes. A prevalent example of this can be seen when Hally and Sam argue over the value of ballroom dancing. Hally fails to recognise its simplistic beauty and consequently claims the activity to be a simple-minded expression of primitive black society. However Sam, through his apparently more refined intellect, is able to convincingly refute Hallys prejudiced argument, exposing the seventeen year olds intellectual inferiority as Hally pompously philosophizes, What is art? WhatRead MorePsychological Theories, Freudian, Object Relational, And The Main Components Of Attachment And Object Relations Theory1660 Words à |à 7 Pagestherapeutic interventions utilized in a clinical setting will be explored through the course of this paper. According to Freudââ¬â¢s conception, there are five stages in psychosexual development, oral, anal, phallic, latency, and genital, which depict the emergence of an individual/clientââ¬â¢s personality throughout the course of life. The oral stage begins from birth and lasts approximately eight to nine months of the infantââ¬â¢s life. The infant begins to feel gratification or pleasure from the mouth regionRead MoreGay Men Experience Higher Rates Of Alcoholism And Addiction Essay1669 Words à |à 7 Pagesan intensely adverse understanding of an event that we may have trouble living a normal life after its occurrence. Some experts have compared what happens in the brain during a traumatic experience to improper coding of data recorded in the most primitive part of the brain (Van Der Kolk, 2014). The way in which traumatic memories get recorded, in contrast to memories tied to the mundane or inconsequential, directly correlates to the kind of emotions that are produced. The se emotions are usuallyRead MoreCore Assumptions1565 Words à |à 7 Pageswords or phrases (expressive aphasia). An autopsy of the brain was carried out after the death of Lesborgne and they found a large left-frontal lobe lesion. After conducting similar research on speech disorder patients, Broca found consistency in the location on the brain and came to the conclusion that the speech production was localised in this area, naming it the Brocaââ¬â¢s Area. (Fancher, Raymond E, 1990) When looking at biochemistry, it is suggested that behaviour is a result of chemical imbalances
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